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| Menopause Symptoms |
Hot FlashesThe exact mechanism of how Hot Flashes occur has not yet been identified. However, it is believed that the disorder occurs at the level of the hypothalamus in the brain.A decrease in the release of sex hormone, in men or women, causes decreased release of opioids, which are responsible for inhibiting the secretion of norepinephrine from the hypothalamus. Hence, there is an increased amount of circulating norepinephrine. The high level of catecholamines in the blood stream causes stimulation of the hypothalamus, which responds with increased Luteinizing Hormone (LH), releasing hormone (LHRH) activity. In addition to increasing LHRH release from the hypothalamus, norepinephrine acts on the thermoregulatory center of the hypothalamus. This cascade results in an increased secretion of luteinizing hormone and the occurrence of hot flashes. While not health-threatening, hot flashes can be very annoying and uncomfortable. As a result of this adverse event, people may discontinue therapy with drugs that may be vital either in providing treatment for their particular disease, or in prolonging the progression of that disease. Also, hot flashes decrease the quality of life of postmenopausal women, as well as certain other patient populations. Although hot flashes are bothersome, they can easily be managed by Dietary Lifestyle Modification. The mainstay of treatment for hot flashes has been hormone replacement therapy (HRT) with its inherent side-effects and increased female-specific cancer risk factors. For this reason, many informed women have elected a natural alternative approach to HRT. It is well known that HRT is not an option in breast cancer survivors, some women with endometrial cancer, and patients with a history of acute vascular thrombosis.
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